It is a metabolic disorder characterised by hyperglycemia,glycosuria, hyperlipemia and ketonamia.
Changes occurs in body
1. Thickening of capillary basement membrane
2. Atherosclerosis
3. Retinopathy
4. Neuropathy
5. Peripheral vascular insufficency
Types
Two major types of Diabetes mellitus
(i) Type I :- Insulin Dependent Diabetes Mellitus (IDDM)
: Insulin is not present in sufficient amount due to the destruction of Beta cell of pancreas
: It is juvenile onset Diabetes Mellitus
(ii) Type II :- Non Insulin Dependent Diabetes Mellitus (NIDDM)
: Insulin is present in sufficient amount
: It is due to reduced insulin receptor
: It is maturity onset Diabetes Mellitus